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A 2005 study demonstrated that both peptide and non-peptide GH secretagogues act through the GHS-R1a receptor but can also function as ghrelin receptor ligands with distinct binding properties, suggesting potential differences in downstream signaling despite shared receptor engagement
Although some authors claim that DPP4 inhibitors are only beneficial in early stages of diabetes, this could be rebutted by the work of Kumar and Gupta (107)
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Patients on GLP-1 medications should focus on consuming adequate protein to support muscle preservation and recovery from workouts
JACC 84(17):16151628 Wallner M, Biber ME, Stolfo D, Sinagra G, Benson L, Dahlstrm U et al (2024) Glucagon-like peptide-1 receptor agonists use and associations with outcomes in heart failure and type 2 diabetes: data from the Swedish Heart Failure and Swedish National Diabetes Registries
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